Description
Product Characteristics:
Aliases: a3 antibody, Atp 6i antibody, Atp6i antibody, ATP6N1C antibody, ATP6V0A3 antibody, ATPase H+ transporting 116kD antibody, OC 116 antibody, OC 116 kDa antibody, OC 116 kDa antibody, OC-116 kDa antibody, OC116 antibody, OPTB 1 antibody, OPTB1 antibody, Osteoclastic proton pump 116 kDa subunit antibody, Specific 116 kDa vacuolar proton pump subunit antibody, Stv 1 antibody, Stv1 antibody, T cell immune regulator 1 antibody, T cell immune regulator 1 ATPase H+ transporting lysosomal V0 subunit A antibody, T cell immune regulator 1 ATPase H+ transporting lysosomal V0 subunit A3 antibody, T cell immune response cDNA 7 antibody, T cell immune response cDNA7 protein antibody, T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a antibody, T-cell immune regulator 1 antibody, T-cell immune response cDNA7 protein antibody, TCIRG 1 antibody, TCIRG1 antibody, TIRC 7 antibody, TIRC7 antibody, V ATPase 116 kDa antibody, V ATPase 116 kDa isoform a3 antibody, V type proton ATPase 116 kDa subunit a antibody, V-ATPase 116 kDa isoform a3 antibody, V-type proton ATPase 116 kDa subunit a isoform 3 antibody, Vacuolar proton translocating ATPase 116 kDa subunit A antibody, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3 antibody, Vph 1 antibody, Vph1 antibody, VPP3_HUMAN antibody
Target Information: Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq, Jul 2008]